notable antibacterial activity against p aeruginosa atcc baa 2108 (ATCC)
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notable antibacterial activity against p aeruginosa atcc baa 2108
Notable Antibacterial Activity Against P Aeruginosa Atcc Baa 2108, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 92 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antibacterial+activity+against+p+aeruginosa/Pseudomonas+aeruginosa+(Schroeter)+Migula/pmc12947026-90-5-11
Average 96 stars, based on 92 article reviews
Notable Antibacterial Activity Against P Aeruginosa Atcc Baa 2108, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 92 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/antibacterial+activity+against+p+aeruginosa/Pseudomonas+aeruginosa+(Schroeter)+Migula/pmc12947026-90-5-11
Average 96 stars, based on 92 article reviews
notable antibacterial activity against p aeruginosa atcc baa 2108 - by Bioz Stars,
2026-09
96/100 stars
Images
1) Product Images from "High-Throughput Screening of FDA-Approved Drugs for Antibacterial and Antibiofilm Activities Against Multidrug-resistant Pseudomonas aeruginosa"
Article Title: High-Throughput Screening of FDA-Approved Drugs for Antibacterial and Antibiofilm Activities Against Multidrug-resistant Pseudomonas aeruginosa
Journal: ACS Omega
doi: 10.1021/acsomega.5c12226
Figure Legend Snippet: Antimicrobial effects of repurposed drugs against MDR P. aeruginosa ATCC BAA-2108. (A) Rifabutin showed dose-dependent antibacterial activity at 1, 2, and 4× MIC. (B) Nafamostat exhibited significant antibacterial activity at 1× MIC, and bactericidal effects at 2× and 4× MIC after 12 h. (C) Tegaserod at 1× and 2× MIC showed sustained inhibition, while 4× MIC exerted rapid bactericidal effects, eradicating bacteria within 4 h and maintaining activity for 12 h. (D) SEM images revealed distinct morphological changes: nafamostat induced aggregation, filamentous adhesions, rough surfaces, and membrane perforation; tegaserod caused membrane wrinkling, contraction, deformation, and content loss; rifabutin-treated cells showed no obvious morphological alterations compared with the control. Red arrows indicate areas of significant morphological change. Scale bars: 0.3 μm (top), 0.15 μm (center), and 0.075 μm (bottom).
Techniques Used: Activity Assay, Inhibition, Bacteria, Membrane, Control
Figure Legend Snippet: Mechanism of antibacterial action of rifabutin against MDR P. aeruginosa . (A, B) NPN probe assay showed concentration-dependent changes in outer membrane permeability of P. aeruginosa ATCC BAA-2108 and 485 treated with rifabutin. (C, D) DiSC3–5 assay showed no significant changes in membrane potential of P. aeruginosa ATCC BAA-2108 and 485 treated with rifabutin. (E, F) PI and Laurdan assays indicated no significant alterations in inner membrane permeability or membrane fluidity, suggesting that rifabutin does not exert its antibacterial effect through disruption of inner membrane integrity. of the antibacterial effect of PF against Staphylococcus aureus . Results are presented as mean ± SD ( n = 3). Statistical significance was evaluated by ordinary one-way ANOVA followed by Dunnett’s (** p < 0.01, **** p < 0.0001) multiple-comparison tests.
Techniques Used: Concentration Assay, Membrane, Permeability, Disruption, Comparison
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